When Kimberly has a violent premonition of a highway pileup she blocks the freeway, keeping a few others meant to die, safe...Or are they? The survivors mysteriously start dying and it's up to Kimberly to stop it before she's next.

When tough-acting loner paramedic Maleek is paired with over-friendly divorcee Wendy, their partnership looks dead on arrival. But pretty soon they're giving each other life support.

After learning that one of their victims, Maya, is still alive, The Strangers return to finish the job. With nowhere to run and no one to trust, Maya soon finds herself in a brutal fight for survival against psychopaths more than willing to kill anyone who stands in their way.