One year after his heroics in Los Angeles, John McClane is an off-duty cop who is the wrong guy in the wrong place at the wrong time. On a snowy Christmas Eve, as he waits for his wife's plane to land at Washington Dulles International Airport, terrorists take over the air traffic control system in a plot to free a South American army general and drug smuggler being flown into the US to face drug charges. It's now up to McClane to take on the terrorists, while coping with an inept airport police chief, an uncooperative anti-terrorist squad, and the life of his wife and everyone else trapped in planes circling overhead.

Ethan Hunt and team continue their search for the terrifying AI known as the Entity — which has infiltrated intelligence networks all over the globe — with the world's governments and a mysterious ghost from Hunt's past on their trail. Joined by new allies and armed with the means to shut the Entity down for good, Hunt is in a race against time to prevent the world as we know it from changing forever.